Thursday, September 07, 2006

Erectile Disfunction

Cardiosource: "Most clinicians are aware of erectile dysfunction (ED) as a clinical entity, but few grasp the enormity of the problem. To varying degrees, it affects about half of all men over the age of 50 and 70% of men over the age of 70.

ED and coronary artery disease (CAD) overlap in risk factors, etiology, and clinical outcomes, with strong evidence that ED is an important marker of vascular disease throughout the arterial tree. Moreover, ED appears to be a marker of silent CAD, perhaps even a sentinal event that precedes frank CAD by several years.

Risk factors present in middle-aged men may portend future development of ED. Whether loss of future sexual function will grab men’s attention in their 30s and 40s, inspiring greater adherence to risk reduction, is unknown. However, for the time being, efforts at prevention may take a back seat to more immediate concerns: a worldwide increase in ED prevalence (associated with rapidly aging populations) combined with new, highly publicized medical treatments is raising challenging issues for clinicians treating these patients.

The Data:
ED affects an estimated 36 million men in the United States, with their ranks growing by more than 600,000 every year.1,2 Worldwide, 152 million men were estimated to be affected in 1995 with that number projected to more than double to 322 million men by 2025.1

The Massachusetts Male Aging Study (MMAS) provided the first relatively unbiased study of the epidemiology of ED and demonstrated that risk increases markedly with age (Slide 1).2,3 This population-based prospective cohort continues to provide normative data on the prevalence of impotence and its physiological and psychosocial correlates in a general population of noninstitutionalized men 40 to 70 years old/.../"

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